Henrique was born in Porto, Portugal. In 1991 became Gastroenterology specialist and defended his PhD, with research on the epidemiology of viral hepatitis.

Full Professor of Epidemiology at Faculty of Medicine, University of Porto;
President of the Institute of Public Health, University of Porto;
President of the National Health Council;
President of the IEA;

Responsible for designing and implementing three on-going Portuguese population-based cohorts which follow adults (EPiPorto), adolescents (EPITeen) and new-borns (G21); these research structures made possible to train a large number of Master and PhD candidates and resulted in multiple publications covering such topics as obesity, cardiovascular diseases, violence and social aspects of ageing besides a continued attention to methodological challenges and a special interest in perinatal epidemiology.